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ARPN Journal of Engineering and Applied Sciences

Synergistic application of response surface methodology and machine learning for strength optimization in 3D-printed PLA composites

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Author Shashwath Patil and Sathish T.
e-ISSN 1819-6608
On Pages 249-258
Volume No. 21
Issue No. 4
Issue Date April 20, 2026
DOI https://doi.org/10.59018/022635
Keywords PLA/HAp composite, 3D printing, biomedical applications, mechanical properties, local materials, sustainable.


Abstract

In the current study, polylactic acid (PLA) filaments reinforced by Squid pen powder (SPP) were 3D printed into filaments and prepared through fused deposition modeling (FDM). The key aim was to maximize tensile strength, and this was done by investigating the concomitant influence of the layer thickness, nozzle temperature, and filler ratio. Response Surface Methodology (RSM) applied a central composite design (CCD) to design regression models and to determine statistically significant factors. The results showed that the most significant impact was on the layer thickness, then the filler ratio, but the nozzle temperature had a relatively weak effect. The optimum material parameters calculated by the RSM were identified to be a layer thickness of 0.2 mm, a nozzle temperature of 220 °C, and a filler ratio of 6 wt.%, which gave the highest tensile strength. To increase predictive accuracy, machine learning (ML) models, such as Support Vector Regression (SVR), Random Forest (RF), and Multi-layer perceptron (MLP) models, were developed. RF performed better, as was supported by a feature importance analysis, which again showed the prevalence of layer thickness. Furthermore, Bayesian optimization combined with RF found similar optimal scenarios and provided a slightly better predictive quality. The integrated RSM-ML system, therefore, provides a powerful tool in the optimization of the tensile strength of 3D-printed polymer composites.

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